Information for Experts

  • 2005
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  • 1992

MEGMILK SNOW BRAND Co., Ltd. has compiled research papers on MBP® of interest to healthcare and nutritional professionals.

Research topic Researcher(s) Publication Date/
Issue No.
A controlled trial of the effect of milk basic protein (MBP®) supplementation on bone metabolism in healthy menopausal women Seiichiro Aoe,
Takao Koyama,
Yasuhiro Toba,
Akira Itabashi, and Yukihiro Takada
Osteoporosis International Vol.16 pp.2123-2128
2005
Cystatin C in Milk Basic Protein (MBP®) and Its Inhibitory Effect on Bone Resorption in Vitro

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Yasuhiro Matsuoka, Atsushi Serizawa,
Tomoe Yoshioka,
Jun-ichi Yamamura, Yoshikazu Morita,
Hiroshi Kawakami, Yasuhiro Toba,
Yukihiro Takada, and Masayoshi Kumegawa
Biosci. Biotechnol. Biochem. Vol.66 pp.2531-2536
2002
Milk Basic Protein (MBP®) Increases Radial Bone Mineral Density in Healthy Adult Women

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Jun-ichi Yamamura, Seiichiro Aoe,
Yasuhiro Toba,
Mutsumi Motouri,
Hiroshi Kawakami, Masayoshi Kumegawa, Akira Itabashi, and Yukihiro Takada
Biosci. Biotechnol. Biochem. Vol.66 pp.702-704
2002
Milk Basic Protein Promotes Bone Formation and Suppresses Bone Resorption in Healthy Adult Men

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Yasuhiro Toba,
Yukihiro Takada,
Yasuhiro Matsuoka, Yoshikazu Morita, Mutsumi Motouri,
Tomoko Hirai,
Toshiaki Suguri,
Seiichiro Aoe,
Hiroshi Kawakami,
Masayoshi Kumegawa, Akira Takeuchi, and
Akira Itabashi
Biosci. Biotechnol. Biochem. Vol.65 pp.1353-1357
2001
Controlled Trial of the Effects of Milk Basic Protein (MBP®) Supplementation on Bone Metabolism in Healthy Adult Women

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Seiichiro Aoe,
Yasuhiro Toba,
Jun-ichi Yamamura, Hiroshi Kawakami, Masatoshi Yahiro, Masayoshi Kumegawa, Akira Itabashi, and Yukihiro Takada
Biosci. Biotechnol. Biochem. Vol.65 pp.913-918
2001
Milk basic protein: a novel protective function of milk against osteoporosis Yasuhiro Toba,
Yukihiro Takada,
Jun-ichi Yamamura, Miyako Tanaka,
Yasuhiro Matsuoka, Hiroshi Kawakami,
Akira Itabashi,
Seiichiro Aoe,
Masayoshi Kumegawa
Bone Vol. 27 pp.403-408
2000
Milk basic protein enhances the bone strength in ovariectomized rats Ken Kato,
Yasuhiro Toba,
Hiroaki Matsuyama,
Jui-ichi Yamamura, Yasuhiro Matsuoka, Hiroshi Kawakami,
Akira Itabashi, Masayoshi Kumegawa, Seiichiro Aoe,
Yukihiro Takada
J. Food Biochem. Vol. 24 pp.467- 476
2000
Bovine milk kininogen fragment 1・2 promotes the proliferation of osteoblastic MC3T3-E1 cells Jun-ichi Yamamura, Yukihiro Takada, Masaaki Goto, Masayoshi Kumegawa, Seiichiro Aoe Biochem. Biophys. Res. Commun. Vol. 269 pp.623-632
2000
High mobility group-like protein in bovine milk stimulates the proliferation of osteoblastic MC3T3-E1 cells Jun-ichi Yamamura, Yukihiro Takada,
Masaaki Goto,
Masayoshi Kumegawa, Seiichiro Aoe
Biochem. Biophys. Res. Commun. Vol. 261 pp.113-117
1999
Whey protein suppresses the osteoclast-mediated bone resorption and osteoclast cell formation Yukihiro Takada, Naomichi Kobayashi, Hiroaki Matsuyama,
Ken Kato,
Jun-ichi Yamamura, Masatoshi Yahiro, Seiichiro Aoe
Int. Dairy Journal Vol. 7 pp.821-825
1997
Whey protein stimulates the proliferation and differentiation of osteoblastic MC3T3-E1 cells Yukihiro Takada,
Seiichiro Aoe,
Masayoshi Kumegawa
Biochem. Biophys. Res. Commun. Vol. 223 pp.445-449
1996
A simple method to assess osteoclast-mediated bone resorption using unfractionated bone cells Yukihiro Takada, Michinori Kusuda,
Kenji Hiura,
Takuya Sato,
Hiroshi Mochizuki, Yoshitaka Nagao,
Michio Tomura, Masatoshi Yahiro, Yoshiyuki Hakeda, Hiroyuki Kawashima, Masayoshi Kumegawa
Bone and Mineral Vol. 17 pp.347-359
1992

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